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Prof. Dr. Köksal ALPTEKİN
Prof. Dr. Köksal ALPTEKİN
Saygıdeğer hocamız ;
Prof. Dr. Köksal ALPTEKİN 'i saygıyla selamlıyoruz.
Türkiye'nin neresinde olursanız olun size önerebileceğimiz en önemli psikiyatrist :
Prof. Dr. Köksal ALPTEKİN
Cumhuriyet Bulvarı No:192
Üstay Apt K.5 D.9
Gündoğdu Meydanı
Alsancak / İzmir
0.232.4224252
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Lucey driscoll sendromu
lucey driscoll sendromu, Geçici ailevi neonatal hiperbilirubinemi olarak
da adlandırılan bu sendromda, hayatın 2-3. gününde başlayan sarılık, 2-3
hafta kadar devam edebilir ve kan değişimi yapabilecek düzeylere erişebilir.
Nedeni tam bilinmemekle beraber, annede glukronil transferazı inhihe eden
bir faktör bulunduğu üzerinde durulmaktadır. Bu faktör doğumdan sonra yavaş
yavaş azalmaya başlar ve 14. günden sonra kaybolur.
Alternate Names
: Transient Familial Neonatal Hyperbilirubinemia
Definition
: Lucey-Driscol Syndrome is an inherited metabolic disorder characterized by
severe hyperbilirubinemia (jaundice) that is present in the infant at
birth.
Overview, Causes, & Risk Factors : Lucey-Driscol syndrome
is thought to be an autosomal recessive inherited disorder. There is an
undetermined enzyme defect in the metabolism of bilirubin. Bilirubin accumulates
and levels escalate rapidly. These high levels are toxic to the brain and can
cause death.
Symptoms & Signs : • jaundice (yellow skin) and
icterus (yellow eyes) of the newborn • lethargy of the newborn • family
history of this disorder • if untreated, seizures and neurologic problems
(kernicterus) may develop
Prevention : Phototherapy can significantly
prevent the potentially serious complications of this disorder.
Diagnosis
& Tests : Blood tests for bilirubin levels are used to confirm the
severity of the jaundice.
Treatment : Phototherapy (with blue light)
is used to treat the high level of bilirubin. An exchange transfusion is
sometimes necessary to treat this disorder.
Prognosis (Expectations)
: If treated, the outcome can be good. Untreated, severe complications
develop because of the accumulation of bilirubin. As indicated by the name
transient, this disorder tends to improve with time after the critical newborn
period.
Complications : Death or severe neurological deficits can
occur if the condition is not treated.
Calling Your Health Care Provider
: Although this problem would most likely be noted immediately after
delivery, call your doctor if you notice your baby's skin turning yellow. There
are other causes for jaundice in the newborn that are easily treated.
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